MRS. SHERLOCK HOLMES tells the true story of Mrs. Grace Humiston, the detective and lawyer who turned her back on New York society life to become one of the nation’s greatest crime fighters during an era when women weren’t even allowed to vote. After graduating from NYU law school, Grace opened a legal clinic in the city for low-income immigrant clients, and quickly established a reputation as a fierce but fair lawyer who was always on the side of the disenfranchised. But despite her many successes in social and criminal justice, Grace began to see chilling connections in the cases she had solved, leading to a final showdown with her most fearsome adversary of all and one of the most powerful men of the 20th century.